What happens if you mix nitazenes with other drugs?

Typically, nitazenes are already mixed with other drugs when they are sold in the U.S., increasing the risk of fatal opioid overdose and other adverse effects.

Nitazenes have been detected in drug samples combined with other synthetic opioids, fentanyl, benzodiazepines, and tranquilizers.

Reviewed and updated by Dr. Sheila P. Vakharia on 04/20/2026.

Next Drug Facts

9 Facts About Cocaine

We need a health approach to cocaine.

Cocaine

Molecular model of cocaine.
A young woman holds a sign that says "End the Drug War."

Sign up for updates from DPA.