How long does fentanyl stay in the system?

Fentanyl effects can be felt for several hours.

Fentanyl effects can be felt for several hours. Effects may be longer when fentanyl skin patches are used, since they slowly release the drug over time.

Someone who recently used fentanyl may test positive on a urine drug test for several days after consuming the drug.

We need a health approach to fentanyl.

Due to drug prohibition, fentanyl is part of the illicit drug supply. Learn more about how drug decriminalization and investing in health, overdose prevention centers, and safer supply can keep people safer.

Reviewed and updated by Jules Netherland, PhD, and Dr. Sheila P. Vakharia on 5/2/2023.