Can you overdose on kratom or 7-OH?

Yes, you can overdose on products sold as kratom and 7-OH.

While not all overdoses are fatal, even non-fatal overdoses can have lasting health effects.

Fatal overdoses from kratom use alone are very rare. Most cases of kratom-involved fatalities o serious adverse effects reported in the United States have involved other drugs.

Kratom and 7-OH appear to respond to naloxone, the opioid overdose reversal medication. It is important for people to never use alone and for bystanders to have access to naloxone so they can respond to an overdose.

People can overdose on products containing kratom or 7-OH by taking too much or more than they anticipated. People with no opioid tolerance are at higher risk for an overdose if they accidentally consume large amounts of these products. However, people with established opioid tolerance are still at risk. They may not know what they are taking or how much since these products are not regulated or tested for adulterants or contaminants. This means people may accidentally consume high doses or mixed products without their knowledge. The risk of an overdose is higher if products are consumed with other opioids or depressant drugs like alcohol, benzodiazepines, or tranquilizers.

Reviewed and updated by Dr. Sheila P. Vakharia on 04/01/2026.

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